1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose
CAS: 68733-20-0
Ref. 3D-MT07137
| 1g | 797.00 € | ||
| 2g | 1,478.00 € | ||
| 100mg | 172.00 € | ||
| 250mg | 290.00 € | ||
| 500mg | 454.00 € |
Product Information
- 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-alpha-D-mannopyranose
- 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose
1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-a-D-mannopyranose (1,3,4,6-TA) is a stable analog of the glycosidic sugar 2,6-dideoxymannose. This compound has been shown to be a potent inhibitor of the synthesis of Neisseria meningitidis capsular polysaccharides and an effective vaccine adjuvant against Mycobacterium tuberculosis. 1,3,4,6-TA is also a competitive inhibitor for the enzyme mycothiol and other thioglycosidic enzymes that are involved in the biosynthesis of mycolic acids. 1,3,4,6-TA was synthesized from 2-(N'-bromoacetamido)-2'-deoxymannose by reaction with sodium azide in acetone. The structure is bicyclic with two
Chemical properties
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