Testosterone b-D-glucuronide

CAS: 1180-25-2

Ref. 3D-MT08814

Product Information

• Name: Testosterone b-D-glucuronide
• Synonyms: Epitestosteroneglucuronide (17beta)-3-Oxoandrost-4-en-17-yl-beta-D-glucopyranosiduronic acid, (17Beta)-3-Oxoandrost-4-En-17-Yl Hexopyranosiduronic Acid, (17beta)-3-oxoandrost-4-en-17-yl beta-D-glucopyranosiduronic acid, (17β)-3-Oxoandrost-4-en-17-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid, Androstane, β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid deriv., Epitestosterone glucuronide, Glucopyranosiduronic acid, 3-oxoandrost-4-en-17β-yl, β-<span class="text-smallcaps">D</span>-, Nsc 92192, Testosterone 17-glucosiduronate, Testosterone 17-glucuronide, Testosterone 17β-(β-<span class="text-smallcaps">D</span>-glucuronide), Testosterone glucopyranuronoside, Testosterone glucosiduronide, Testosterone glucuronate, Testosterone glucuronide, Testosterone glucuronide conjugate, Testosterone glucuronoside, beta-D-Glucopyranosiduronic acid, (17beta)-3-oxoandrost-4-en-17-yl, β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, (17β)-3-oxoandrost-4-en-17-yl

Description

Testosterone b-D-glucuronide (TbG) is a clinically relevant metabolite of testosterone. It is the glucuronide conjugate of testosterone, which means that it is formed by the addition of a glucuronic acid molecule to the hydroxyl group at position 17. TbG has been detected in human plasma, urine and feces. The concentration of TbG in these fluids reflects the levels of total testosterone in the body. TbG may also be used as a biomarker for assessing exposure to nonsteroidal anti-inflammatory drugs (NSAIDs). It has been shown that NSAIDs can form conjugates with glucuronic acid, leading to elevated concentrations of TbG in urine samples.
TbG binds to monoclonal antibodies and is therefore used as a sample preparation step prior to analysis by polymerase chain reaction or flow assay.

• Brand: Biosynth

Chemical properties

• Molecular weight: 464.55 g/mol
• Formula: C₂₅H₃₆O₈
• Purity: Min. 95%
• Color/Form: White Powder