Tri-b-GalNAc-gly-biotin

Ref. 3D-MT184244

Product Information

• Name: Tri-b-GalNAc-gly-biotin
• Synonyms: Tris-β-GalNAc-Gly-biotinBiotin-Gly-tris-beta-GalNAcTrebler GalNAc BiotinTri-GalNAc-β-Gly-BiotinTriantennary GalNAc beta glycine biotinBiotin-Gly-tris-beta-GalNAc
• Brand: Biosynth
• Description: Tri-b-GalNAc-Gly-biotin is used for studying ASGPR-mediated processes. This molecule combines three terminal beta-N-acetylgalactosamine (GalNAc) sugars for efficient ASGPR binding with a glycine (Gly) spacer and a biotin moiety. The GalNAc moiety facilitates specific targeting to hepatocytes, while the glycine spacer provides flexibility. The terminal biotin group serves a dual purpose: it allows for straightforward purification of ASGPR-interacting molecules via affinity chromatography and enables further bioconjugation via established streptavidin-biotin conjugation strategies. This combination makes tri-b-GalNAc-Gly-biotin valuable for isolating ASGPR-binding ligands from complex mixtures, studying ASGPR-ligand interactions, and potentially developing targeted probes for in vitro and in vivo applications.

Chemical properties

• Molecular weight: 1,698.93 g/mol
• Formula: C₇₃H₁₂₇N₁₃O₃₀S
• Purity: Min. 95%