Product Information
- Tri-GalNAc (Cbz
- peracetylated)Tris-GalNAc (Cbz
- peracetylated)Tris-β-GalNAc-Cbz (perac)Tris-GalNAcAc3-Cbztri-β-GalNAcAc3-NHCbz Triantennary β-GalNAcAc3-NHCbz
This peracetylated tri-b-GalNAcAc3-NHCbz, a triantennary N-acetylgalactosamine (GalNAc) ligand with protected functionalities, serves as a valuable building block for ASGPR-targeted therapies. Its three branches or arms, each ending in a GalNAc sugar, ensure strong binding to hepatocyte ASGPR. However, the key feature lies in its protective groups: acetylated sugars allow for controlled removal to expose reactive sites for conjugation, while the Cbz-protected amine provides stability and can be selectively cleaved to introduce a reactive amine group for further biomolecule attachment, ultimately enabling researchers to tailor Tri-b-GalNAcAc3-NHCbz into customized conjugates for specific therapeutic applications.
Chemical properties
Technical inquiry about: 3D-MT184246 Tri-b-GalNAcAc3-NHCbz
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