Tri-b-GalNAc-b-alanine-PEG3-DBCO

Ref. 3D-MT184252

Product Information

• Name: Tri-b-GalNAc-b-alanine-PEG3-DBCO
• Synonyms: Trivalent GalNAc-β-Ala-PEG3-DBCO(β-D-GalNAc-sp)3-NHC(O)-β-Ala-PEG3-DBCOTris-GalNAc-beta-Ala-PEG3-DBCOTris-β-GalNAc-β-Alanine-PEG3 -DibenzocyclooctyneTriantennary β-D-GalNAc triethyleneglycol Dibenzocyclooctyne
• Brand: Biosynth
• Description: Very similar to tri-b-GalNAc-b-alanine-PEG4-DBCO (which contains a PEG4 instead of PEG3 as a spacer), this cluster, tri-b-galnac-b-alanine-peg3-DBCO, contains also three terminal beta-N-acetylgalactosamine (GalNAc) sugars for efficient ASGPR binding. The beta-alanine linker separates the GalNAc unit from a PEG3 spacer, improving water solubility and potentially influencing pharmacokinetics. The terminal amine group serves as a reactive handle for conjugation to various biomolecules via amide bond formation. This multifunctional combination makes tri-b-GalNAc-b-alanine-PEG3-amine a versatile tool for researchers developing targeted therapies and diagnostics exploiting the ASGPR pathway.

Chemical properties

• Molecular weight: 1,977.2 g/mol
• Formula: C₉₂H₁₄₅N₁₃O₃₄
• Purity: Min. 95%