UDP-D-glucuronide ammonium salt

CAS: 43195-60-4

Ref. 3D-MU46744

Product Information

• Name: UDP-D-glucuronide ammonium salt
• Synonyms: UDP-GlcAUridine 5'-diphosphate glucuronic acid ammonium saltUridine[5?]diphospho[1]-?-D-glucopyranosuronic acid ammonium saltUDPG A
• Brand: Biosynth
• Description: UDP-D-glucuronide ammonium salt is a drug that is used for the treatment of estrogen-dependent cancers. It is an inhibitor of human UDP-glucuronosyltransferase, an enzyme that catalyzes the glucuronidation of estrone and other substrates. The binding affinity of UDP-D-glucuronide ammonium salt can be increased by mutating the enzyme to increase its kinetic rate. This drug has been shown to inhibit estrogen production in recombinant human liver cells as well as in human liver cells. Mutations in the gene encoding this enzyme have also been associated with variations in estrogen levels, specifically high rates.

Chemical properties

• Molecular weight: 580.29 g/mol
• Formula: C₁₅H₂₂N₂O₁₈P₂·xNH₃
• Purity: Min. 95%