Norketamine hydrochloride

CAS: 79499-59-5

Ref. 3D-N-1300

Product Information

• Name: Norketamine hydrochloride
• Synonyms: 2-Amino-2-(2-chlorophenyl)cyclohexanone hydrochloride
• Brand: Biosynth
• Description: Norketamine hydrochloride is a chemical compound that acts as the predominant metabolite of ketamine, which is both synthesized and isolated through the metabolic processes of ketamine in the liver. It exhibits action primarily as an NMDA receptor antagonist, thereby modulating glutamatergic neurotransmission. This mode of action implies that norketamine hydrochloride can have dissociative and anesthetic effects similar to its parent compound, though typically considered to be less potent.The research applications of norketamine hydrochloride are vast, primarily in studying its effects on the central nervous system. Scientists often investigate its pharmacokinetics, pharmacodynamics, and potential therapeutic effects for conditions such as depression and chronic pain. It is also explored in the context of neuroprotection and in understanding the broader pharmacological profile of ketamine derivatives. Overall, its implications in the modulation of synaptic plasticity and neurochemical pathways make it a compound of significant interest within neuropharmacological research.

Chemical properties

• Molecular weight: 260.16 g/mol
• Formula: C₁₂H₁₅Cl₂NO
• Purity: Min. 99.0 Area-%