5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine
CAS: 51247-09-7
Ref. 3D-NA02562
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Product Information
- 1-(5-O-acetyl-2,3-dideoxy-a-D-erythro-pentofuranosyl)uracil
5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine is a novel nucleoside analogue that is an activator of the innate immune system. It is used for the treatment of cancer and viral infections. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has been shown to have anticancer activity against pancreatic, lung, breast, prostate, colon, and leukemia cells in vitro. This drug also inhibits influenza virus A/WSN/33 replication in cell culture by blocking the RNA polymerase complex at the initiation stage. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has also been shown to be active against herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1).
Chemical properties
Technical inquiry about: 3D-NA02562 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine
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