8-Azaadenosine

CAS: 10299-44-2

Ref. 3D-NA02698

Product Information

• Name: 8-Azaadenosine
• Synonyms: 3-Beta-D-Ribofuranosyl-3H-1,2,3-Triazolo(4,5-D)Pyrimidin-7-Amine, 3-Triazolo(4,5-D)Pyrimidin-7-Amine,3-Beta-D-Ribofuranosyl-3H-2, 3-pentofuranosyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine, 3-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine, 3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine, 3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 3H-v-Triazolo[4,5-d]pyrimidine, 7-amino-3-beta.-D-ribofuranosyl-, 3H-v-Triazolo[4,5-d]pyrimidine, 7-amino-3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 5-D)Pyrimidine,7-Amino-3-Beta-D-Ribofuranosyl-3H-V-Triazolo(, 7-Amino-3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-v-triazolo[4,5-d]pyrimidine, NSC 72961

Description

8-Azaadenosine is a purine nucleoside that is used as a template for DNA replication. The zwitterionic form of 8-Azaadenosine is found in plants and is converted to the charged form by enzymatic reactions. 8-Azaadenosine binds to the dna template strand and acts as a hydrogen bond donor, which stabilizes the transition state of the reaction and inhibits enzyme activity. This drug has been shown to affect polymerase chain reaction (PCR) by inhibiting DNA synthesis and it has been used in cancer cell lines with resistant mutants, such as Herpes simplex virus type 1 (HSV1).

• Brand: Biosynth

Chemical properties

• Molecular weight: 268.23 g/mol
• Formula: C₉H₁₂N₆O₄
• Purity: Min. 97 Area-%
• Color/Form: Off-White Powder