2'-Azido-2'-deoxyadenosine

CAS: 58699-61-9

Ref. 3D-NA02932

Product Information

• Name: 2'-Azido-2'-deoxyadenosine
• Synonyms: 2'-Azido-D-adenosine2'-Deoxy-2'-azido-D-adenosine
• Brand: Biosynth
• Description: 2'-Azido-2'-deoxyadenosine is a synthetic nucleoside analog of adenosine in which the 2'-hydroxyl group of the ribose sugar is replaced by an azido group (–N₃), and the 3'- and 5'-hydroxyl groups remain intact. This modification confers unique chemical properties, including the ability to participate in bioorthogonal "click" chemistry reactions, particularly azide-alkyne cycloadditions, making it useful for labeling and tracking nucleic acids in biochemical studies. Additionally, the azido substitution can influence enzymatic recognition and incorporation by polymerases, allowing its use in studying nucleic acid metabolism, drug design, and therapeutic nucleoside analog development.

Chemical properties

• Molecular weight: 292.25 g/mol
• Formula: C₁₀H₁₂N₈O₃
• Purity: Min. 95%
• Color/Form: Powder