Product Information
Name:5-Azacytidine
Synonyms:
- Azacitidine
- 5-AzaCVidazaCC-486
Brand:Biosynth
Description:An azanucleoside and epigenetic modulator that interferes with nucleic acid metabolism. The compound gets incorporated into RNA and inhibits ribonucleotide reductase subunit RRM2 in leukemia cell lines. Intracellularly, 5-azacytidine can get converted into 2′-deoxy-5-azacytidine (decitabine) and subsequently incorporated in DNA, where it irreversibly inhibits DNMT1 methyltransferase. In human epithelial cell lines, this compound decreases Src-activated expression of a histone chaperone CAF1 and inhibits cell motility and invasiveness.
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Chemical properties
Molecular weight:244.21 g/mol
Formula:C8H12N4O5
Purity:Min. 95%
Color/Form:White Off-White Powder
Technical inquiry about: 5-Azacytidine
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