Decitabine

CAS: 2353-33-5

Ref. 3D-NA02969

Product Information

• Name: Decitabine
• Synonyms: 5-Aza-2'-deoxycytidine 4-Amino-1-(2-deoxy-b-D-ribofuranosyl)-1,3 ,5-triazin-2(1H)-one 5-Aza-2'-deoxy-D-cytidine 2'-Deoxy-5-azacytidin, 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-, 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-, 2'-Deoxy-5-azacytidine, 2'-Desoxy-5-Azacytidine, 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin, 4-Amino-1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one, 4-Amino-1-(2-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-1,3,5-triazin-2(1H)-one, 4-Amino-1-(2-desoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-on, 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one, 4-amino-1-(2-deoxypentofuranosyl)-1,3,5-triazin-2(1H)-one, 4-amino-1-(2-desoxi-β-D-erythro-pentofuranosil)-1,3,5-triazin-2(1H)-ona, 4-amino-1-(2-desoxy-β-D-erythro-pentofurannosyl)-1,3,5-triazine-2(1H)-one, 5-Azadeoxycytidine, A 2232, DAC, Dacogen, Decitabine & its intermediates, Decitabine & its intermediates (R&D), Decitabine intermediates, Nsc 127716, Nsc127716, s-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-, s-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-, β-Decitabine, 5-Aza-2′-deoxycytidine

Description

A synthetic cytosine analogue that incorporates into DNA and prevents DNA methylation via DNA (cytosine-5)-methyltransferase 1 (DNMT1) inhibition. Demonstrated potent anti-leukaemic effects attributed to cell cycle arrest and induction of apoptosis. Has anti-growth effects on solid tumor cell lines.

• Brand: Biosynth

Chemical properties

• Molecular weight: 228.21 g/mol
• Formula: C₈H₁₂N₄O₄
• Purity: Min. 98 Area-%
• Color/Form: White Powder