8-Aminoadenosine
CAS: 3868-33-5
Ref. 3D-NA05711
| 25mg | 238.00 € | ||
| 50mg | 357.00 € | ||
| 100mg | 497.00 € | ||
| 250mg | 948.00 € | ||
| 500mg | 1,430.00 € |
Product Information
- 8-Amino-D-adenosine
- 9H-Purine, 6,8-diamino-9-.beta.-D-ribofuranosyl-
- Adenosine, 8-Amino-
8-Aminoadenosine can be used to study the mitochondrial membrane potential, a critical cellular function in which ATP levels are maintained by oxidative phosphorylation. 8-Aminoadenosine is one of the few drugs that have been shown to increase ATP levels in cells. It does this by increasing the permeability of mitochondria membranes and the rate of electron transport from complex I to complex II. The reaction mechanism is thought to involve an intramolecular hydrogen transfer from NADH to 8-aminoadenosine, forming an unstable intermediate that undergoes a conformational change that enables it to react with oxygen. 8-Aminoadenosine has been shown as an effective treatment for certain autoimmune diseases and resistant breast cancer. It also has anti-inflammatory effects, as well as receptor activity against HIV infection and Toll-like receptors.
Chemical properties
Technical inquiry about: 3D-NA05711 8-Aminoadenosine
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