3'-Azido-2',3'-dideoxyuridine

CAS: 84472-85-5

Ref. 3D-NA05737

Product Information

• Name: 3'-Azido-2',3'-dideoxyuridine
• Synonyms: 3’-beta-Azido-2’,3’-dideoxyuridine3'-Azido-2',3'-dideoxy-D-uridine
• Brand: Biosynth
• Description: 3'-Azido-2',3'-dideoxyuridine is an analog of the nucleoside dideoxyuridine that inhibits HIV replication. It has a high inhibitory dose and low toxicity. 3'-Azido-2',3'-dideoxyuridine is converted to its active form, 3'-azido-2',3'-dideoxythymidine (AZT), by dephosphorylation in human serum. AZT inhibits HIV replication by competing with the natural substrate for viral DNA polymerase, thereby inhibiting synthesis of viral DNA. 3'-Azido-2',3'-dideoxyuridine has been shown to be effective against hepatitis B virus and hepatitis C virus in cell cultures.

Chemical properties

• Molecular weight: 253.21 g/mol
• Formula: C₉H₁₁N₅O₄
• Purity: Min. 95%
• Color/Form: Off-White Powder