5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine

Ref. 3D-NA06300

Product Information

• Name: 5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine
• Brand: Biosynth
• Description: 5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine is a novel anticancer agent that has been shown to be active against leukemia, lymphoma and myeloma. The compound is a nucleoside analogue that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have antiviral activity in vitro against herpes simplex virus type 1 and type 2, influenza A virus and HIV. 5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine can also inhibit protein synthesis by blocking the incorporation of amino acids into protein. This drug is synthesized from 3',5'-dideoxyuridine (dU) and fluoroacetyl chloride to produce 5'-O-p-anisoyl-3',5'-difluoroacetyl dU (ADUF). ADUF is then reacted with anisole to produce 5

Chemical properties

• Molecular weight: 378.4 g/mol
• Formula: C₁₈H₁₉FN₂O₆
• Purity: Min. 95%