5-Acetoxymethyl-2'-deoxycytidine

Ref. 3D-NA12830

Product Information

• Name: 5-Acetoxymethyl-2'-deoxycytidine
• Brand: Biosynth
• Description: 5-Acetoxymethyl-2'-deoxycytidine (5-AO-dC) is a nucleoside that is used as an anticancer agent. It is a modified form of cytidine and has been shown to be effective in the treatment of cancer cells. 5-AO-dC inhibits the production of DNA by binding to deoxyribonucleotide triphosphate and preventing its conversion into diphosphate, thereby inhibiting DNA synthesis. The drug also inhibits viral replication by binding to viral RNA and interfering with the synthesis of viral proteins. 5-AO-dC may also inhibit HIV replication by competing with HIV reverse transcriptase for the incorporation of deoxyadenosine monophosphate into DNA.5-AO-dC is not active against bacteria or fungi but it does bind to human ribonucleosides and can inhibit the synthesis of both DNA and RNA in human cells.

Chemical properties

• Molecular weight: 299.28 g/mol
• Formula: C₁₂H₁₇N₃O₆
• Purity: Min. 95%
• InChI: InChI=1S/C12H17N3O6/c1-6(17)20-5-7-3-15(12(19)14-11(7)13)10-2-8(18)9(4-16)21-10/h3,8-10,16,18H,2,4-5H2,1H3,(H2,13,14,19)/t8?,9-,10-/m1/s1
• InChI key: InChIKey=FQZGQCJTQWZSMO-VXRWAFEHSA-N
• SMILES: CC(=O)OCc1cn([C@H]2CC(O)[C@@H](CO)O2)c(=O)nc1N