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4'-Azidothymidine 5-triphosphate
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4'-Azidothymidine 5-triphosphate

CAS: 140158-13-0

Ref. 3D-NA13340

1gTo inquire
Estimated delivery in United States, on Friday 27 Dec 2024

Product Information

Name:
4'-Azidothymidine 5-triphosphate
Synonyms:
  • Adrt 5'-triphosphate
  • Adrt-TP
  • Thymidine 5'-(tetrahydrogen triphosphate),4'-azido-
  • [(2R,3S,5R)-2-azido-3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
Description:

4'-Azidothymidine 5-triphosphate (4AZTTP) is a deoxyribonucleoside that has been synthesized as an analog to thymidine. It has potent inhibitory activity against human immunodeficiency virus (HIV), and has been shown to be more effective than 2',3'-dideoxyinosine in inhibiting HIV replication. 4AZTTP inhibits the viral enzyme reverse transcriptase, which is crucial for the replication of HIV. This drug is activated by cellular enzymes and phosphorylated to 4'-azidothymidine 5'-triphosphate monophosphate, which can then bind to the viral DNA template and inhibit synthesis of RNA strands. The kinetic properties of 4AZTTP have been studied in detail using human lymphocytes as a model system for HIV infection.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
523.18 g/mol
Formula:
C10H16N5O14P3
Purity:
Min. 95%
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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