5'-Amino-2',5'-dideoxy-2'-fluorouridine
Ref. 3D-NA137611
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Product Information
5'-Amino-2',5'-dideoxy-2'-fluorouridine is an antiviral drug that is synthesized from the natural compound 5'-deoxy-5'-amino-2',5'-dideoxyuridine. The modified deoxyribonucleosides are activated by phosphorylation and can be incorporated into DNA by DNA polymerase, which prevents viral replication. The monophosphate form of this compound is used in cancer chemotherapy to inhibit the synthesis of RNA and proteins necessary for cell division. 5'-Amino-2',5'-dideoxy-2'-fluorouridine has been shown to be a potent anticancer agent, with activity against a variety of human tumor cell lines.
Chemical properties
Technical inquiry about: 3D-NA137611 5'-Amino-2',5'-dideoxy-2'-fluorouridine
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