2’-O-Acetyl-8-bromo-7-cyano-7-deaza-3’-deoxy-3’-fluoro-5’-O-toluoyladenosine
Ref. 3D-NA162935
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Product Information
2'-O-Acetyl-8-bromo-7-cyano-7-deaza-3'-deoxy-3'-fluoro-5'-O-[toluoyl]adenosine (ABT) is a modified nucleoside that has anticancer and antiviral properties. ABT is a monophosphate nucleotide with an acetyl group at the 2' position of the ribose and a toluoyl group on the 7 position of the adenine moiety. In vitro, ABT inhibits tumor proliferation in breast cancer cells and suppresses viral replication in herpes simplex virus type 1 (HSV1) infected cells. ABT also has potential as a novel therapeutic agent for treating cancers and other diseases caused by HSV1 infection.
Chemical properties
Technical inquiry about: 3D-NA162935 2’-O-Acetyl-8-bromo-7-cyano-7-deaza-3’-deoxy-3’-fluoro-5’-O-toluoyladenosine
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