![6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine](https://static.cymitquimica.com/products/3D/img/NA162940.png "Click to enlarge")
6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine
Ref. 3D-NA162940
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Product Information
6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine (6ADRP) is a synthetic nucleoside that is used as an activator of ribonucleosides and diphosphates in DNA synthesis. 6ADRP has antiviral activity against HIV and herpes simplex virus type 1. It binds to the viral DNA polymerase and prevents the addition of nucleotides to the growing DNA strand. 6ADRP is phosphorylated by T7 kinase to form the active metabolite, 6-amino-1-(2'-deoxy-[alpha]-D-ribofuranosyl)-5'-triphosphate (6ATP), which inhibits viral replication by preventing the formation of RNA primers.
Chemical properties
Technical inquiry about: 3D-NA162940 6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine
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