5’-Azido-2’,5’-dideoxyuridine

CAS: 35959-37-6

Ref. 3D-NA163034

Product Information

• Name: 5’-Azido-2’,5’-dideoxyuridine
• Brand: Biosynth
• Description: 5’-Azido-2’,5’-dideoxyuridine (5ADU) is a pyrimidine nucleoside that has been used to treat cancer. It is converted to 5-azidouracil which inhibits the synthesis of thymidylate, an essential component of DNA. 5ADU is also active against herpes virus and can be used as an antiviral agent. This drug has been shown to protect against radiation damage by inhibiting the formation of free radicals. The protonation of 5ADU leads to a stereochemical rearrangement that prevents the formation of free radicals. 5ADU does not inhibit bacterial enzymes, but it does have some effect on viruses, such as herpes virus, because they contain DNA or RNA similar to human cells.

Chemical properties

• Molecular weight: 253.21 g/mol
• Formula: C₉H₁₁N₅O₄
• Purity: Min. 95%