Product Information
Name:2',3'-Anhydrothymidine
Synonyms:
- 1-(2,3-Anhydro-b-D-lyxofuranosyl)-thymine
Brand:Biosynth
Description:2',3'-Anhydrothymidine is a nucleoside analogue that has been shown to inhibit HIV-1 transcriptase and polymerase by binding to the enzyme's active site. It also inhibits DNA synthesis in human cells and inhibits the growth of E. coli. 2',3'-Anhydrothymidine is a prodrug that can be taken up by cells, where it is converted into an epoxide, which then binds to the enzyme's active site. This prevents the enzyme from catalyzing reactions and terminating DNA synthesis at the correct point during transcription. 2',3'-Anhydrothymidine may also have immunodeficiency-related benefits due to its ability to bind more tightly to dsDNA than natural nucleotides, causing termination of RNA synthesis at the wrong point.
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Chemical properties
Molecular weight:240.21 g/mol
Formula:C10H12N2O5
Purity:Min. 95%
Technical inquiry about: 2',3'-Anhydrothymidine
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