7-(Aminomethyl)-7-deazaadenosine

CAS: 55470-42-3

Ref. 3D-NA166561

Product Information

• Name: 7-(Aminomethyl)-7-deazaadenosine
• Synonyms: 4-Amino-7-b-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-methanamine
• Brand: Biosynth
• Description: 7-(Aminomethyl)-7-deazaadenosine is a nucleoside that has antiviral and anticancer properties. It is a novel compound, and its synthesis involves the use of activated 2′-deoxyribonucleosides. This compound is synthesized by reacting 7-amino-7-deazaguanine with an appropriate phosphoramidite at room temperature in the presence of an activator such as ammonium hydroxide or pyridine. The product can be purified by recrystallization from methanol, followed by chromatography on silica gel using a gradient elution system. The purity of this compound can be determined by HPLC analysis with UV detection at 254 nm.br>br>

Chemical properties

• Molecular weight: 295.29 g/mol
• Formula: C₁₂H₁₇N₅O₄
• Purity: Min. 95%
• InChI: InChI=1S/C12H17N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,1,3,13H2,(H2,14,15,16)
• InChI key: InChIKey=AFMKIRMZLLCSAV-UHFFFAOYSA-N
• SMILES: NCc1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12