2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine

CAS: 143653-60-5

Ref. 3D-NA31581

Product Information

• Name: 2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine
• Brand: Biosynth
• Description: 2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine (ABT-888) is a nucleoside analog that inhibits DNA synthesis and RNA transcription. It has been shown to induce apoptosis in human cancer cells, including leukemia, lymphoma and breast cancer cells. ABT-888 also has antiviral activity against herpes simplex virus type 1 and 2, vaccinia virus, and vesicular stomatitis virus.

Chemical properties

• Molecular weight: 388.37 g/mol
• Formula: C₁₉H₂₀N₂O₇
• Purity: Min. 95%
• InChI: InChI=1S/C19H20N2O7/c1-11-9-21(19(25)20-16(11)23)17-15(27-12(2)22)8-14(28-17)10-26-18(24)13-6-4-3-5-7-13/h3-7,9,14-15,17H,8,10H2,1-2H3,(H,20,23,25)/t14-,15+,17+/m0/s1
• InChI key: InChIKey=XTVCWWXMHSBNPN-ZMSDIMECSA-N
• SMILES: CC(=O)O[C@@H]1C[C@@H](COC(=O)c2ccccc2)O[C@H]1n1cc(C)c(=O)[nH]c1=O