5'-Azido-2',5'-dideoxycytidine

CAS: 4803-88-7

Ref. 3D-NA45440

Product Information

• Name: 5'-Azido-2',5'-dideoxycytidine
• Brand: Biosynth
• Description: 5'-Azido-2',5'-dideoxycytidine is a macrocyclic nucleoside that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication. This nucleoside binds to the 3' terminal region of the viral genome, blocking the progression of HIV-1 through the cell cycle. 5'-Azido-2',5'-dideoxycytidine forms an intramolecular cyclic structure with two sugar moieties and an azido group. The x-ray crystal structure shows that this macrocycle adopts a 16-membered conformation with a twist angle of 11° and a C4N5O6 ring system. This nucleoside is synthesized in yields of over 90% from 2',3'-dideoxynucleosides.

Chemical properties

• Molecular weight: 252.23 g/mol
• Formula: C₉H₁₂N₆O₃
• Purity: Min. 95%
• Color/Form: Powder