5'-Azido-5'-deoxyadenosine

CAS: 737-76-8

Ref. 3D-NA46264

Product Information

• Name: 5'-Azido-5'-deoxyadenosine
• Brand: Biosynth
• Description: 5'-Azido-5'-deoxyadenosine (Aza-dA) is an adenosine analog that inhibits the deamination of S-adenosylhomocysteine to form adenosine. It has been shown to be more potent than 2-chloroadenosine and inactivates the enzyme s-adenosylhomocysteine hydrolase, which is responsible for the conversion of S-adenosylhomocysteine to adenosine. This leads to decreased levels of adenosine and increased levels of s-adensoylhomocysteine. Aza-dA has been shown to inhibit tumor growth and induce apoptosis in rat hepatocytes. In addition, it is a halogenated molecule that can be used as a modifying agent.

Chemical properties

• Molecular weight: 292.25 g/mol
• Formula: C₁₀H₁₂N₈O₃
• Purity: Min. 95%
• Color/Form: Powder