2-Amino-4-(4-bromophenyl)pyrimidine

CAS: 392326-81-7

Ref. 3D-NA57404

Product Information

• Name: 2-Amino-4-(4-bromophenyl)pyrimidine
• Synonyms: 4-(4-Bromophenyl)pyrimidin-2-amine

Description

2-Amino-4-(4-bromophenyl)pyrimidine is a phosphoramidite, modified nucleoside. It is an antiviral and anticancer agent that inhibits DNA synthesis. 2-Amino-4-(4-bromophenyl)pyrimidine is a novel nucleotide analog with the ability to inhibit replication of RNA and DNA in vitro. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), cytomegalovirus (CMV), and HIV in cell culture. Furthermore, this phosphoramidite has been shown to have no detectable toxicity in mice at doses up to 2000 mg/kg.

• Brand: Biosynth

Chemical properties

• Molecular weight: 250.09 g/mol
• Formula: C₁₀H₈BrN₃
• Purity: Min. 95%
• InChI: InChI=1S/C10H8BrN3/c11-8-3-1-7(2-4-8)9-5-6-13-10(12)14-9/h1-6H,(H2,12,13,14)
• InChI key: InChIKey=ULMOYCJVOJTPCJ-UHFFFAOYSA-N
• SMILES: Nc1nccc(-c2ccc(Br)cc2)n1