2-Aminopyrimidine-5-boronic acid

CAS: 936250-22-5

Ref. 3D-NA57424

Product Information

• Name: 2-Aminopyrimidine-5-boronic acid
• Synonyms: 2-Amino-5-boronopyrimidine, (2-Aminopyrimidin-5-yl)boronic acid, 2-Amino-pyrimidine-5-boronic acid, 2-Aminopyrimidine-5-boronicacid, B-(2-Amino-5-pyrimidinyl)boronic acid, boronic acid, B-(2-amino-5-pyrimidinyl)-

Description

2-Aminopyrimidine-5-boronic acid is a synthetic compound that has been shown to inhibit the activity of cellulase enzymes in vitro. It also has neuroprotective effects and potent inhibition against cancer cells. 2-Aminopyrimidine-5-boronic acid's mechanism of action is reversible covalent, meaning that it reacts with DNA by forming an N2-(2'-aminopyrimidine) adduct with guanine at position 6 in the purine ring. This reaction inhibits DNA synthesis, leading to cell death. 2-Aminopyrimidine-5-boronic acid is not currently being used as a cancer therapy, but it is being researched for its potential use in cancer treatments.

• Brand: Biosynth

Chemical properties

• Molecular weight: 138.92 g/mol
• Formula: C₄H₆BN₃O₂
• Purity: Min. 95%
• InChI: InChI=1S/C4H6BN3O2/c6-4-7-1-3(2-8-4)5(9)10/h1-2,9-10H,(H2,6,7,8)
• InChI key: InChIKey=CGHYQZASLKERLV-UHFFFAOYSA-N
• SMILES: Nc1ncc(B(O)O)cn1