1-[2-(6-Aminopurin-9-yl)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-1-yl]ethanone

CAS: 14062-45-4

Ref. 3D-NA71841

Product Information

• Name: 1-[2-(6-Aminopurin-9-yl)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-1-yl]ethanone
• Synonyms: 4'-Acetamido-4'-deoxyadenosine
• Brand: Biosynth
• Description: 1-[2-(6-Aminopurin-9-yl)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-1-yl]ethanone is a synthetic nucleoside analog that can be used as an activator or inhibitor of ribonucleic acid (RNA) synthesis. It is also a novel anticancer and antiviral agent. 1-[2-(6-Aminopurin-9-yl)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-1-yl]ethanone has shown anti tumor activity in animal models of skin cancer and leukemia. This compound has been shown to inhibit the replication of the human immunodeficiency virus type 1 in vitro and in vivo.

Chemical properties

• Molecular weight: 308.29 g/mol
• Formula: C₁₂H₁₆N₆O₄
• Purity: Min. 95%
• InChI: InChI=1S/C12H16N6O4/c1-5(20)18-6(2-19)8(21)9(22)12(18)17-4-16-7-10(13)14-3-15-11(7)17/h3-4,6,8-9,12,19,21-22H,2H2,1H3,(H2,13,14,15)
• InChI key: InChIKey=LHLODVQMOGVFMU-UHFFFAOYSA-N
• SMILES: CC(=O)N1C(CO)C(O)C(O)C1n1cnc2c(N)ncnc21