3,7-Dimethyluric acid

CAS: 13087-49-5

Ref. 3D-NAA08749

Product Information

• Name: 3,7-Dimethyluric acid
• Brand: Biosynth
• Description: 3,7-Dimethyluric acid (3,7-DMUA) is a purine derivative that is found in the human liver. It is metabolized by p-450 enzymes to form 3,7-dihydroxypurine and 3,7-dimethylxanthine. The carbonyl group of the compound reacts with reactive oxygen species to form a reactive carbonyl intermediate. This reactive intermediate may be responsible for the formation of DNA adducts or for the generation of oxidative metabolites that are cytotoxic. 3,7-DMUA has been shown to inhibit protein synthesis in vitro and cause cancer in vivo in mice. The effect on protein synthesis may be due to its ability to inhibit cytochrome P450 enzymes. 3,7-DMUA also has an effect on body mass index (BMI), which may be due to its ability to induce apoptosis and inhibit cell proliferation by inhibiting protein synthesis.

Chemical properties

• Molecular weight: 196.16 g/mol
• Formula: C₇H₈N₄O₃
• Purity: Min. 95%