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Ethyl 1H-tetrazole-5-acetate

CAS:

Ref. 3D-NAA61637

10g
417.00€
100g
1,106.00€
Ethyl 1H-tetrazole-5-acetate
Biosynth

Product Information

Name:Ethyl 1H-tetrazole-5-acetate
Brand:Biosynth
Description:

Ethyl 1H-tetrazole-5-acetate (ETZA) is a ligand that binds to the active site of prolyl hydroxylase, which is an enzyme involved in collagen synthesis. ETZA inhibits the activity of this enzyme by binding to its heme cofactor, leading to a decrease in the production of collagen and thus inhibiting tumor growth. It has been shown that ETZA has no effect on healthy cells or normal tissues. In vitro studies have shown that ETZA can inhibit cancer cell growth and cisplatin resistance in vivo. ETZA also has a structural similarity to chloride ions and thus may be able to inhibit chloride channels such as those found in cancer cells.

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Chemical properties

Molecular weight:156.14 g/mol
Formula:C5H8N4O2
Purity:Min. 95%

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