Product Information
3-Bromo-6-chloroquinoline is a cisplatin analogue that is used in the treatment of cancer. It has been shown to have cytotoxic effects against human T47D cells, an estrogen receptor positive cell line, by binding to DNA and interfering with DNA replication. 3-Bromo-6-chloroquinoline has also been shown to have significant cytotoxic activity against the Mcf-7 breast cancer cell line. It binds to the proximal region of the human cytochrome P450 1A2 enzyme and blocks its ability to metabolize drugs, which prevents the activation of certain anticancer agents. This drug also inhibits the synthesis of RNA and protein, leading to cancer cell death.
Chemical properties
Technical inquiry about: 3D-NAA66965 3-bromo-6-chloroquinoline
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