Product Information
Name:5-Hydroxypyrazine-2-carboxamide
Brand:Biosynth
Description:5-Hydroxypyrazine-2-carboxamide is a prodrug of pyrazinamide, an anti-tuberculosis drug. It is metabolized to pyrazinoic acid in the liver and excreted in the urine. The concentration of 5-hydroxypyrazine-2-carboxamide in the blood plasma is very low and no significant accumulation has been observed. In experiments with rats, 5-hydroxypyrazine-2-carboxamide was shown to be well tolerated and did not produce any adverse effects at doses up to 500 mg/kg orally. It also effectively inhibited bacterial growth in vitro and showed good activity against Mycobacterium tuberculosis and Mycobacterium avium complex.5-Hydroxypyrazine-2-carboxamide is used for the treatment of tuberculosis in pediatric patients who cannot tolerate other antitubercular drugs or who have failed to respond satisfactorily to other
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Chemical properties
Molecular weight:139.11 g/mol
Formula:C5H5N3O2
Purity:Min. 95%
Color/Form:Powder
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