5-Bromo-2'-deoxyuridine

CAS: 59-14-3

Ref. 3D-NB06315

Product Information

• Name: 5-Bromo-2'-deoxyuridine
• Synonyms: 2'-Deoxy-5-bromouridine5-Bromo-2'-deoxy-D-uridine
• Brand: Biosynth
• Description: 5-Bromo-2'-deoxyuridine (5-BrDU) is a nitrate reductase inhibitor that prevents the reduction of nitrate to nitrite by inhibiting the enzyme nitrate reductase. It is a genotoxic agent that has been shown to cause DNA damage and cell death in vitro. 5-BrDU has been shown to induce preconditioning in vivo, reducing neuronal injury after ischemia. This drug also binds to NMDA receptors and may be useful as a model system for studying neurodegenerative diseases such as Alzheimer's disease. 5-BrDU has been shown to inhibit the polymerase chain reaction in wild-type strains of bacteria, but not in strains with a mutation in their DNA gyrase genes.

Chemical properties

• Molecular weight: 307.1 g/mol
• Formula: C₉H₁₁BrN₂O₅
• Purity: Min. 99 Area-%
• Color/Form: White Off-White Powder