8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Sp-isomer sodium salt

CAS: 127634-20-2

Ref. 3D-NB08953

Product Information

• Name: 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Sp-isomer sodium salt
• Synonyms: Sp-8-Br-cAMP8-Bromo-D-adenosine 3',5'-cyclic monophosphothiaoate, Sp-isomer sodium salt
• Brand: Biosynth
• Description: 8-Bromoadenosine 3',5'-cyclic monophosphate is a nucleotide analog that binds to RNA polymerase and blocks the elongation of RNA. It has been shown to stimulate axonal regeneration in the rat spinal cord, by increasing the level of glutamate in the extracellular space. 8-Bromoadenosine 3',5'-cyclic monophosphate also stimulates nerve growth factor (NGF) production and activates protein kinase C (PKC). This drug also inhibits apoptosis by inhibiting the activity of Mcl-1 protein, which is involved in mitochondrial membrane permeability.

Chemical properties

• Molecular weight: 446.51 g/mol
• Formula: C₁₀H₁₀BrN₅O₅PS·Na
• Purity: Min. 95%
• Color/Form: White to off-white solid.