Product Information
Name:2',5'-Bis-O-(triphenylmethyl)uridine
Brand:Biosynth
Description:2',5'-Bis-O-(triphenylmethyl)uridine is a synthetic nucleoside that is used in the treatment of leukemia. It is used as an analogue of uridine and guanosine, and is converted to these compounds by decarboxylase enzymes. 2',5'-Bis-O-(triphenylmethyl)uridine has been shown to inhibit the proliferation of L1210 cells in vitro and in vivo, but not normal cells. 2',5'-Bis-O-(triphenylmethyl)uridine also inhibits DNA synthesis by inhibiting the enzyme hydroxylase and carboxylate, which are involved in purine metabolism. This drug binds to the ribonucleotide reductase enzyme and blocks its activity, thereby inhibiting RNA synthesis.
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Chemical properties
Purity:Min. 95%
Technical inquiry about: 2',5'-Bis-O-(triphenylmethyl)uridine
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