2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine

CAS: 182007-86-9

Ref. 3D-NB57544

Product Information

• Name: 2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine
• Brand: Biosynth
• Description: 2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine is an antiviral nucleoside that has been shown to inhibit the activity of a novel human DNA polymerase. This nucleoside is a monophosphate, CAS No. 182007-86-9, and is highly reactive with various phosphoramidites. 2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine is synthesized by the reaction of guanosine with dimethylchlorosilane in the presence of triethylamine. It can be used as a building block for synthesis of oligodeoxyribonucleotides or modified ribonucleotides.

Chemical properties

• Molecular weight: 467.59 g/mol
• Formula: C₂₀H₃₃N₅O₆Si
• Purity: Min. 95%
• Color/Form: Powder