4-Formyl-3-hydroxynaphthalene-2-carboxylic acid

CAS: 38399-46-1

Ref. 3D-NBA39946

Product Information

• Name: 4-Formyl-3-hydroxynaphthalene-2-carboxylic acid
• Synonyms: 2-Hydroxy-1-naphthaldehyde-3-carboxylic acid, 2-Hydroxy-3-carboxy-1-naphthaldehyde, 2-Naphthalenecarboxylic Acid, 4-Formyl-3-Hydroxy-, 2-Naphthoic acid, 4-formyl-3-hydroxy-, 3-Carboxy-2-hydroxy-1-naphthaldehyde, 4-Formyl-3-hydroxy-2-naphthalenecarboxylic acid, 4-Formyl-3-hydroxy-2-naphthoic acid

Description

4-Formyl-3-hydroxynaphthalene-2-carboxylic acid (4FHN) is an antibacterial agent. It is bacteriostatic and has been shown to be effective against gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa, but not against gram-positive bacteria such as Staphylococcus aureus. 4FHN was found to inhibit the growth of both gram-positive and gram-negative bacteria by binding to the ribosomal RNA in the bacterial cell wall, thereby inhibiting protein synthesis and cell division. 4FHN also shows antimicrobial activity due to its ability to form stable hydrazones with nucleophilic centers in the bacterial cell wall. These compounds react with cellular macromolecules, leading to cell death.

• Brand: Biosynth

Chemical properties

• Molecular weight: 216.19 g/mol
• Formula: C₁₂H₈O₄
• Purity: Min. 95%