2-[4-(benzyloxy)phenoxy]acetic acid

CAS: 38559-92-1

Ref. 3D-NBA55992

Product Information

• Name: 2-[4-(benzyloxy)phenoxy]acetic acid
• Brand: Biosynth
• Description: GW7647 is a novel compound that has been shown to activate Peroxisome proliferator-activated receptor gamma (PPARγ), which is a nuclear hormone receptor involved in lipid metabolism and the development of insulin resistance. GW7647 activates PPARγ by binding to the ligand-binding domain of the receptor and activating transcriptional activity. This activation was observed in human cells, as well as subtypes of human PPARγ. It has been shown to be selective for PPARγ over other receptors, such as Peroxisome proliferator-activated receptor delta (PPARδ). GW7647 acts on dyslipidemia by lowering triglyceride levels and increasing HDL cholesterol levels without affecting LDL cholesterol levels. This drug has also been shown to have lipid-lowering effects in mice fed a high-fat diet.

Chemical properties

• Molecular weight: 258.27 g/mol
• Formula: C₁₅H₁₄O₄
• Purity: Min. 95%