Cytidine 5'-monophosphate disodium salt

CAS: 6757-06-8

Ref. 3D-NC05637

Product Information

• Name: Cytidine 5'-monophosphate disodium salt
• Synonyms: 5'-CMP.2NaD-Cytidine 5'-monophosphate disodium salt, 5'-CMP disodium salt, 5'-Cytidylic acid, disodium salt, 5′-Cytidylic acid, sodium salt (1:2), CMP disodium salt, Ccris 7313, Citidine-5-monophosphate disodium salt, Cytidine 5'MP, disodium salt, Cytidine 5′-monophosphate sodium, Cytidine monophosphate disodium salt, Disodium 5'-CMP, Disodium 5'-cytidilate, Disodium 5′-cytidylate, Disodium CMP, Disodium cytidine 5'-monophosphate, Disodium cytidine 5'-phosphate, Nsc 20259, Sodium 5′-cytidylate, disodium 5'-O-phosphonatocytidine

Description

Cytidine 5'-monophosphate disodium salt (CMPDS) is a prodrug that is converted to cytidine 5'-monophosphate, an active form, in the acidic environment of cancer cells. CMPDS has been shown to inhibit the growth of squamous carcinoma and other solid tumours by binding to survivin, which regulates cell growth and apoptosis. CMPDS also inhibits the activity of matrix metalloproteinases-9 (MMP-9), an enzyme that promotes tumor growth by breaking down connective tissue. This drug can be used as a therapeutic agent for treatment of congestive heart failure due to its ability to increase mitochondrial membrane potential and decrease myocardial infarct size.

• Brand: Biosynth

Chemical properties

• Molecular weight: 367.16 g/mol
• Formula: C₉H₁₂N₃Na₂O₈P
• Purity: Min. 95 Area-%
• Color/Form: White Powder