Clevudine

CAS: 163252-36-6

Ref. 3D-NC09470

Product Information

• Name: Clevudine
• Synonyms: Levovir2'-Deoxy-2'-fluoro-5-methylarabinofuranosyluracil1-(2'-Deoxy-2'-fluoro-β-L-arabinofuranosyl)-5-methyluracil
• Brand: Biosynth
• Description: Clevudine is a synthetic pyrimidine analogue effective against the hepatitis B virus (HBV). Once inside the cell, it is converted into its active forms, clevudine monophosphate and clevudine triphosphate. The triphosphate form competes with thymidine to be incorporated into viral DNA, leading to DNA chain termination and inhibition of the HBV DNA polymerase (reverse transcriptase). Due to its long half-life, clevudine significantly reduces covalently closed circular DNA (cccDNA), making relapse less likely after treatment ends.

Chemical properties

• Molecular weight: 260.22 g/mol
• Formula: C₁₀H₁₃FN₂O₅
• Purity: Min. 95%
• Color/Form: White Powder