2-Chloro-3-deazaadenosine

CAS: 40656-71-1

Ref. 3D-NC09808

Product Information

• Name: 2-Chloro-3-deazaadenosine
• Synonyms: 4-Amino-6-chloro-1-b-D-ribofuranosylimidazo[4,5-c]pyridine, 1H-imidazo[4,5-c]pyridin-4-amine, 6-chloro-1-pentofuranosyl-

Description

2-Chloro-3-deazaadenosine is an antiviral drug that inhibits the synthesis of DNA by acting as a competitive inhibitor for adenosine. It has been shown to be effective in the treatment of hepatitis B virus and herpes simplex virus infections. 2-Chloro-3-deazaadenosine prevents the incorporation of the natural nucleoside adenosine into DNA, which leads to inhibition of viral replication and cell division. This drug also has been shown to inactivate liver cells in bovines, which may account for its toxicity. The synthesis of 2-chloroadenosine is difficult and laborious due to its glycosylation, making it more expensive than other analogues that are more easily synthesized.

• Brand: Biosynth

Chemical properties

• Molecular weight: 300.7 g/mol
• Formula: C₁₁H₁₃ClN₄O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H13ClN4O4/c12-6-1-4-7(10(13)15-6)14-3-16(4)11-9(19)8(18)5(2-17)20-11/h1,3,5,8-9,11,17-19H,2H2,(H2,13,15)
• InChI key: InChIKey=LIDWXUGNGGWNEU-UHFFFAOYSA-N
• SMILES: Nc1nc(Cl)cc2c1ncn2C1OC(CO)C(O)C1O