8-Chloroadenosine 3',5'-cyclic monophosphate
CAS: 41941-56-4
Ref. 3D-NC10380
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire |
Product Information
- 8-Cl-cAMP
- Adenosine, 8-chloro-, cyclic 3′,5′-(hydrogen phosphate)
- 8-Chloroadenosine 3′,5′-cyclic phosphate
- 8-Chloro-cyclic AMP
- 8-Chloro-cAMP
- 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.
8-Chloroadenosine 3',5'-cyclic monophosphate (8-CAM) is a potent inducer of the mitochondrial membrane potential. It has been shown to have cytotoxic effects on human myeloma cell line, HL-60 cells, and fetal bovine serum. 8-CAM has shown anticancer properties in solid tumours in mice. It was also found to be toxic to human carcinoma cell lines and synergistic with other pharmacological agents, such as doxorubicin. 8-CAM has been shown to have immunosuppressive effects in animal models and may be a potential therapeutic agent for autoimmune diseases.
Chemical properties
Technical inquiry about: 3D-NC10380 8-Chloroadenosine 3',5'-cyclic monophosphate
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