2-Chloro-4-hydroxy-5-fluoropyrimidine

CAS: 155-12-4

Ref. 3D-NC11515

Product Information

• Name: 2-Chloro-4-hydroxy-5-fluoropyrimidine
• Synonyms: 2-Chloro-5-Fluoropyrimidin-4-One, 2-Chloro-5-fluoro-pyrimidin-4-ol, 4(1H)-Pyrimidinone, 2-chloro-5-fluoro- (9CI), 2-chloro-5-fluoropyrimidin-4(3H)-one

Description

2-Chloro-4-hydroxy-5-fluoropyrimidine is a nucleoside with antiviral and anticancer activity. It has shown to be an effective agent against HIV, herpes virus and human papilloma virus. 2-Chloro-4-hydroxy-5-fluoropyrimidine inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which catalyzes the formation of diphosphate from monophosphate. In addition, it inhibits protein synthesis by inhibiting ribonucleotide reductase, which catalyzes the conversion of ribonucleotides to deoxyribonucleotides.

• Brand: Biosynth

Chemical properties

• Molecular weight: 148.52 g/mol
• Formula: C₄H₂ClFN₂O
• Purity: Min. 95%
• InChI: InChI=1S/C4H2ClFN2O/c5-4-7-1-2(6)3(9)8-4/h1H,(H,7,8,9)
• InChI key: InChIKey=FHTLMXYURUPWJB-UHFFFAOYSA-N
• SMILES: O=c1[nH]c(Cl)ncc1F