Cyclic adenosine 5'-diphosphate ribose ammonium salt

CAS: 119340-53-3

Ref. 3D-NC11582

Product Information

• Name: Cyclic adenosine 5'-diphosphate ribose ammonium salt
• Synonyms: ADP-cyclo[N1:1'']-ribosecADPRcADP-ribose, (2R,3R,4S,5R,13R,14S,15R,16R,24Z)-24-imino-7,9,11,25,26-pentaoxa-1,17,19,22-tetraaza-8,10-diphosphapentacyclo[18.3.1.1~2,5~.1~13,16~.0~17,21~]hexacosa-18,20,22-triene-3,4,8,10,14,15-hexol 8,10-dioxide (non-preferred name), Adenosine 5′-(trihydrogen diphosphate), 1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, intramol. P′,5′′-ester, Adp-Cyclo-[N1:1']-Ribose, Cadpr, Cyclic Adenosine 5'-Diphosphate Ribose, Cyclic Adenosine Diphosphate Ribose Sodium Salt, Cyclic Adenosine Diphosphate-Ribose, Cyclic Adp-Ribose, Cyclic Adpr, N-Alpha-D-Riofuranosyl-P',5'-Ester Adenosine 5'-(Trihydrogen Diphosphate), cAPD ribose, MeSH ID: D036563, Adenosine 5′-(trihydrogen diphosphate), 1-β-D-ribofuranosyl-, intramol. P′,5′′-ester

Description

Cyclic Adenosine 5'-diphosphate ribose ammonium salt (CADPRAM) is a potent inhibitor of cyclic nucleotide phosphodiesterases (PDEs). CADPRAM reversibly inhibits PDEs and prevents the hydrolysis of cAMP. This inhibition can lead to an increase in cytosolic Ca2+. CADPRAM also inhibits polymerase chain reaction, which is why it cannot be used for the treatment of infectious diseases. CADPRAM has been shown to inhibit the activity of enzymes that are known to play a role in clinical pathology, such as adenylate cyclase and phosphodiesterase type 3.

• Brand: Biosynth

Chemical properties

• Molecular weight: 558.33 g/mol
• Formula: C₁₅H₂₁N₅O₁₃P₂·NH₃
• Purity: Min. 95%
• Color/Form: White solid.