2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine

CAS: 120225-75-4

Ref. 3D-NC16518

Product Information

• Name: 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine
• Synonyms: 1-(6-Amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-b-D-ribofuranuronamide2-Chloro-2',3'-O-isopropylidene adenosine-5'-N-ethylcarboxamide
• Brand: Biosynth
• Description: 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine is an antiviral agent that inhibits the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). It is a synthetic, modified nucleoside. 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine has been shown to be active against human tumor cell lines in vitro and in vivo. The compound inhibits the activity of DNA polymerase and RNA polymerase by competitive inhibition of the enzyme phosphoramidite. 2CECA has also been shown to have anticancer properties as it induces apoptosis in cancer cells.

Chemical properties

• Molecular weight: 382.8 g/mol
• Formula: C₁₅H₁₉ClN₆O₄
• Purity: Min. 95%
• InChI: InChI=1S/C15H19ClN6O4/c1-4-18-12(23)8-7-9(26-15(2,3)25-7)13(24-8)22-5-19-6-10(17)20-14(16)21-11(6)22/h5,7-9,13H,4H2,1-3H3,(H,18,23)(H2,17,20,21)
• InChI key: InChIKey=CHPHKXXDQSHQKC-UHFFFAOYSA-N
• SMILES: CCNC(=O)C1OC(n2cnc3c(N)nc(Cl)nc32)C2OC(C)(C)OC12