Product Information
- (+)-Baclofen hydrochloride
- (R)-4-Amino-3-(4-chlorophenyl)butanoic acid hydrochloride
- (R)-4-Amino-3-(4-chlorophenyl)butyric acid hydrochloride
- (R)-Baclofen monohydrochloride
- Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-, (betaR)-, hydrochloride (1:1)
- Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride (1:1), (βR)-
- Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride, (R)-
- Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride, (βR)-
- R-Baclofen hydrochloride
- d-Baclofen hydrochloride
- See more synonyms
- (3R)-4-Amino-3-(4-chlorophenyl)butanoic acid hydrochloride (1:1)
R(+)-Baclofen.Hydrochloride is a GABA analogue that stimulates the GABA-benzodiazepine receptor complex and produces antinociception. It has been shown to be effective against diabetic neuropathy in rats, with no observed side effects. R(+)-Baclofen.Hydrochloride is used for the treatment of trigeminal neuralgia, butyric acid induced hyperalgesia and chronic constriction injury in rats. The main mechanism of action of R(+)-Baclofen.Hydrochloride is its ability to activate the benzodiazepine receptor by binding to it, which leads to mitochondrial membrane potential depolarization and an increase in the release of gamma-aminobutyric acid (GABA) from neurons.
Chemical properties
Technical inquiry about: 3D-NCA70155 R(+)-Baclofen.Hydrochloride
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