Product Information
BX-430 is a potent and selective inhibitor of voltage-gated sodium channels, including Nav1.8, which is primarily expressed in the central nervous system. This molecule has been shown to inhibit bladder contractility in rat models. BX-430 inhibits uptake of cations through non-selective cations channels and blocks the activation of p2y receptors, leading to an increase in intracellular calcium levels. It has also been shown to have anti-inflammatory effects by inhibiting microglia activation and suppressing production of pro-inflammatory cytokines such as TNFα and ILβ.
Chemical properties
Technical inquiry about: 3D-NCB30970 BX 430
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