Product Information
CGM-097 is a potent antitumor agent that targets senescent cells. It is a monoclonal antibody that specifically binds to the apoptosis protein, which prevents its translocation to the nucleus and induces apoptosis. CGM-097 has been shown to have potent antitumor activity in vivo models of melanoma and BCR-ABL positive leukemia. CGM-097 has been shown to be chemically stable in vitro and in vivo, with no significant toxicity observed at higher doses. The drug’s synergistic effects are due to its ability to target both tumor cells and their surrounding microenvironment, as well as upregulating genes involved in cell death and immune response.
Chemical properties
Technical inquiry about: 3D-NCC36354 CGM-097
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