Product Information
7-BIA is a potent non-competitive phosphatase inhibitor. It inhibits tyrosine phosphatases by binding to the enzyme's ligand-binding site and preventing substrate from binding. This drug has been shown to inhibit phosphatases in vivo and in vitro studies, including cyclopentyl phosphatase, p38 MAP kinase, and PI3K. 7-BIA also blocks cAMP synthesis and reduces the activity of protein kinase A. 7-BIA is a competitive ligand for the pharmacophore site of the enzyme PP2A, which is found in both brain cells and platelets.
Chemical properties
Technical inquiry about: 3D-NCC40349 7-BIA
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